Health Sciences

Rare Mutations May Not Always Spur Breast Cancer on Their Own

Results of a new laboratory study suggest that some rare “missense” mutations in the HER2 gene are apparently not — on their own — capable of causing breast cancer growth or spread. In a related finding, the Johns Hopkins research team said such mutations, which are found in about 5 percent of breast cancers, may, thus, also fail to predict response to anti-cancer drugs…(Read the full story)

Researchers Link Organ Transplant Drug to Rise in Rare Lymphoma

A study led by Johns Hopkins researchers has linked the immunosuppressive drug mycophenolate mofetil (MMF) to an increased risk of central nervous system (CNS) lymphoma in solid organ transplant patients. But the same study also found that another class of immunosuppressive drugs, called calcineurin inhibitors (CNIs), appears to protect transplant patients against this rare form of lymphoma. (Read the full story)